Protein-Protein Docking: Fast and user-friendly data mining and clustering software is now here!
Explore ARCTIC-3D (Automatic Retrieval and ClusTering of Interfaces in Complexes from 3D structural information).
ARCTIC-3D a novel tool to retrieve your data and rationalize the interface information associated with the protein input data. Once provided with protein input data (a uniprot ID, a FASTA file, or a PDB file), ARCTIC-3D queries the PDBe-graph database through its graph-API, extracting the available information about the protein of interest. Then it applies hierarchical clustering to the calculated similarity values of interfaces projected on the protein structure.
By applying the concept of recognition entropy, the interface-specific restraints generated by ARCTIC-3D should be useful to any modelling software that can make use of such information for model generation and/ or scoring.
ARCTIC-3D, available both as a standalone code and as a as a user-friendly web service. The information generated by ARCTIC-3D helps in understanding the structural relationships between protein interfaces, identifying conserved or distinct interaction patterns, and gaining insights into the functional implications of protein-protein interactions.
Explore ARCTIC-3D software at https://lnkd.in/gWg42ysJ (Free)
Website: https://lnkd.in/gMMtKRtR.
